| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-06-12 | HENDERSON MICHAEL THOMAS Chief Executive Officer | Sale | -20,000 | -1.79%1,095,987 | $83.38 | $1,667,622 | View SEC filing | |
| 2026-06-05 | Dambkowski Carl Chief Medical Officer | Sale | -5,500 | -2.60%205,648 | $78.71 | $432,905 | View SEC filing | |
| 2026-05-08 | Dambkowski Carl Chief Medical Officer | Sale | -5,500 | -2.59%207,023 | $84.14 | $462,784 | View SEC filing | |
| 2026-05-04 | Henderson Jane Chief Financial Officer | Sale | -2,000 | -1.14%173,371 | $82.04 | $164,080 | View SEC filing | |
| 2026-04-17 | Henderson Jane Chief Financial Officer | Sale | -2,000 | -1.13%175,371 | $90.00 | $180,000 | View SEC filing | |
| 2026-04-10 | HENDERSON MICHAEL THOMAS Chief Executive Officer | Sale | -20,000 | -1.73%1,132,987 | $82.58 | $1,651,664 | View SEC filing | |
| 2026-04-03 | Dambkowski Carl Chief Medical Officer | Sale | -5,500 | -2.57%208,398 | $84.84 | $466,619 | View SEC filing | |
| 2026-04-03 | Henderson Jane Chief Financial Officer | Sale | -2,000 | -1.12%177,371 | $85.01 | $170,020 | View SEC filing | |
| 2026-03-27 | Henderson Jane Chief Financial Officer | Sale | -2,000 | -1.10%179,371 | $85.00 | $170,000 | View SEC filing | |
| 2026-03-13 | HENDERSON MICHAEL THOMAS Chief Executive Officer | Sale | -20,000 | -1.71%1,152,987 | $74.78 | $1,495,605 | View SEC filing | |
| 2026-03-06 | Dambkowski Carl Chief Medical Officer | Sale | -5,500 | -2.55%209,773 | $71.06 | $390,825 | View SEC filing | |
| 2026-03-04 | Henderson Jane Chief Financial Officer | Sale | -2,000 | -1.09%181,371 | $70.22 | $140,431 | View SEC filing | |
| 2026-02-13 | HENDERSON MICHAEL THOMAS Chief Executive Officer | Sale | -20,000 | -1.68%1,172,987 | $63.35 | $1,266,953 | View SEC filing | |
| 2026-02-04 | Dambkowski Carl Chief Medical Officer | Sale | -5,500 | -2.54%211,148 | $65.79 | $361,860 | View SEC filing | |
| 2026-02-04 | Henderson Jane Chief Financial Officer | Sale | -2,000 | -1.08%183,371 | $65.81 | $131,630 | View SEC filing | |
| 2026-01-22 | Harwin Peter Evan Director | Sale | -1,750,000 | -85.42%298,647 | $76.30 | $133,525,000 | View SEC filing | |
| 2026-01-16 | HENDERSON MICHAEL THOMAS Chief Executive Officer | Sale | -20,000 | -1.65%1,192,987 | $81.11 | $1,622,159 | View SEC filing | |
| 2026-01-09 | Dambkowski Carl Chief Medical Officer | Sale | -18,700 | -8.09%212,523 | $77.84 | $1,455,613 | View SEC filing | |
| 2026-01-06 | Henderson Jane Chief Financial Officer | Sale | -8,000 | -4.14%185,371 | $76.14 | $609,146 | View SEC filing | |
| 2025-12-23 | Henderson Jane Chief Financial Officer | Sale | -1,500 | -0.77%193,371 | $80.00 | $120,000 | View SEC filing | |
| 2025-12-12 | HENDERSON MICHAEL THOMAS Chief Executive Officer | Sale | -20,000 | -1.62%1,212,987 | $75.38 | $1,507,657 | View SEC filing | |
| 2025-12-05 | Dambkowski Carl Chief Medical Officer | Sale | -10,900 | -3.87%271,108 | $75.00 | $817,500 | View SEC filing | |
| 2025-12-05 | Henderson Jane Chief Financial Officer | Sale | -1,500 | -0.76%194,871 | $75.00 | $112,500 | View SEC filing | |
| 2025-12-05 | HENDERSON MICHAEL THOMAS Chief Executive Officer | Sale | -40,000 | -3.14%1,232,987 | $75.01 | $3,000,400 | View SEC filing | |
| 2025-11-28 | Henderson Jane Chief Financial Officer | Sale | -1,500 | -0.76%196,371 | $70.00 | $105,000 | View SEC filing |
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