| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership changeShares owned | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-06-22 | Scholl Hendrik Peter Chief Medical Officer | Sale | -10,000 | -40.00%15,000 | $145.24 | $1,452,435 | View SEC filing | |
| 2026-06-17 | Scholl Hendrik Peter Chief Medical Officer | Sale | -10,000 | -28.57%25,000 | $140.57 | $1,405,729 | View SEC filing | |
| 2026-05-08 | MATA NATHAN L. Chief Scientific Officer | Sale | -666 | -100.00%0 | $153.21 | $102,039 | View SEC filing | |
| 2026-05-07 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -60.02%666 | $153.84 | $153,839 | View SEC filing | |
| 2026-05-06 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -37.51%1,666 | $155.50 | $155,502 | View SEC filing | |
| 2026-05-05 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -27.28%2,666 | $155.64 | $155,636 | View SEC filing | |
| 2026-05-04 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -21.43%3,666 | $155.78 | $155,778 | View SEC filing | |
| 2026-05-01 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -17.65%4,666 | $156.97 | $156,973 | View SEC filing | |
| 2026-04-30 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -15.00%5,666 | $155.82 | $155,817 | View SEC filing | |
| 2026-04-29 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -13.04%6,666 | $159.16 | $159,162 | View SEC filing | |
| 2026-04-27 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -11.54%7,666 | $162.64 | $162,641 | View SEC filing | |
| 2026-04-24 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -10.35%8,666 | $159.56 | $159,556 | View SEC filing | |
| 2026-04-24 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -9.38%9,666 | $166.28 | $166,284 | View SEC filing | |
| 2026-04-23 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -8.57%10,666 | $170.38 | $170,384 | View SEC filing | |
| 2026-04-22 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -7.90%11,666 | $166.00 | $166,000 | View SEC filing | |
| 2026-04-21 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -7.32%12,666 | $163.59 | $163,595 | View SEC filing | |
| 2026-04-20 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -6.82%13,666 | $161.63 | $161,630 | View SEC filing | |
| 2026-04-20 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -6.38%14,666 | $160.38 | $160,381 | View SEC filing | |
| 2026-04-16 | MATA NATHAN L. Chief Scientific Officer | Sale | -1,000 | -6.00%15,666 | $168.30 | $168,298 | View SEC filing | |
| 2026-04-13 | Lin Yu-Hsin Chief Executive Officer | Sale | -9,200 | -5.11%170,934 | $181.45 | $1,669,339 | View SEC filing | |
| 2026-04-13 | Chen Wan-Shan Director | Sale | -1,100 | -10.79%9,096 | $180.43 | $198,473 | View SEC filing | |
| 2026-04-13 | Chuang Hao-Yuan Chief Financial Officer | Sale | -6,200 | -6.20%93,800 | $181.50 | $1,125,303 | View SEC filing |
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