| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-06-11 | De Vre Raymond Director | Sale | -2,605 | -2.98%84,811 | $2.37 | $6,174 | View SEC filing | |
| 2026-02-25 | Lutz Stefan Chief Scientific Officer | Sale | -5,862 | -4.30%130,421 | $1.13 | $6,641 | View SEC filing | |
| 2026-02-09 | Lutz Stefan Chief Scientific Officer | Sale | -2,492 | -1.80%136,283 | $1.31 | $3,257 | View SEC filing | |
| 2026-02-09 | Erbez Georgia See Remarks | Sale | -3,826 | -5.42%66,810 | $1.31 | $5,001 | View SEC filing | |
| 2026-02-09 | MOORE ALISON President and CEO | Sale | -3,826 | -1.50%250,506 | $1.31 | $5,001 | View SEC filing | |
| 2026-01-08 | Lutz Stefan CSO | Sale | -4,685 | -3.27%138,775 | $1.70 | $7,950 | View SEC filing | |
| 2025-12-15 | Opaleye Management Inc. 10% Owner | Sale | -514,341 | -4.83%10,134,989 | $1.71 | $877,846 | View SEC filing | |
| 2025-12-15 | Opaleye Management Inc. 10% Owner | Sale | -1,063,211 | -8.31%11,731,779 | $1.76 | $1,868,198 | View SEC filing | |
| 2025-12-01 | Opaleye Management Inc. 10% Owner | Sale | -217,705 | -2.10%10,134,989 | $1.71 | $877,846 | View SEC filing | |
| 2025-11-25 | WOLF DENNIS P Director | Sale | -8,952 | -6.05%138,951 | $1.56 | $13,988 | View SEC filing | |
| 2025-11-14 | Opaleye Management Inc. 10% Owner | Sale | +697,541 | +7.01%10,649,330 | $1.94 | $2,101,032 | View SEC filing | |
| 2025-11-13 | De Vre Raymond Director | Sale | -1,413 | -1.59%87,416 | $1.74 | $2,459 | View SEC filing | |
| 2025-11-12 | Opaleye Management Inc. 10% Owner | Sale | -469,847 | -3.85%11,731,779 | $1.76 | $1,868,198 | View SEC filing | |
| 2025-10-15 | MOORE ALISON Chief Technical Officer | Sale | -6,239 | -3.55%169,332 | $2.51 | $15,629 | View SEC filing | |
| 2025-10-15 | Erbez Georgia Chief Financial Officer | Sale | -6,239 | -8.12%70,636 | $2.50 | $15,629 | View SEC filing | |
| 2025-08-04 | Opaleye Management Inc. 10% Owner | Purchase | +85,000 | +0.68%12,545,000 | $2.68 | $227,921 | View SEC filing | |
| 2025-07-31 | Opaleye Management Inc. 10% Owner | Purchase | +10,000 | +0.08%12,460,000 | $2.82 | $28,161 | View SEC filing | |
| 2025-07-22 | Opaleye Management Inc. 10% Owner | Purchase | +100,000 | +0.81%12,450,000 | $2.82 | $282,000 | View SEC filing | |
| 2025-07-01 | Opaleye Management Inc. 10% Owner | Purchase | +100,000 | +0.82%12,350,000 | $2.39 | $239,000 | View SEC filing | |
| 2025-06-16 | Opaleye Management Inc. 10% Owner | Purchase | +250,000 | +2.08%12,250,000 | $2.24 | $560,009 | View SEC filing | |
| 2025-05-28 | Opaleye Management Inc. 10% Owner | Purchase | +2,325,000 | +24.03%12,000,000 | $2.36 | $5,487,000 | View SEC filing | |
| 2025-05-02 | Opaleye Management Inc. 10% Owner | Purchase | +45,000 | +0.47%9,675,000 | $2.31 | $104,096 | View SEC filing | |
| 2025-04-29 | Opaleye Management Inc. 10% Owner | Purchase | +25,000 | +0.26%9,630,000 | $2.24 | $55,915 | View SEC filing | |
| 2025-04-17 | Opaleye Management Inc. 10% Owner | Purchase | +140,000 | +1.48%9,605,000 | $2.13 | $298,773 | View SEC filing | |
| 2025-04-09 | Opaleye Management Inc. 10% Owner | Purchase | +100,000 | +1.07%9,465,000 | $1.98 | $198,380 | View SEC filing |
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