| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-06-15 | Moore David Scott Director | Purchase | +21,700 | +100.00%21,700 | $11.53 | $250,236 | View SEC filing | |
| 2026-05-20 | MILLER RICHARD A MD President and CEO | Purchase | +6,932 | +0.58%1,195,035 | $12.04 | $83,453 | View SEC filing | |
| 2025-07-01 | ORBIMED ADVISORS LLC Director, 10% Owner | Sale | -1,176,332 | -14.10%7,165,006 | $4.16 | $4,891,894 | View SEC filing | |
| 2025-07-01 | Thompson Peter A. Director, 10% Owner | Sale | -1,176,332 | -14.10%7,165,006 | $4.16 | $4,891,894 | View SEC filing | |
| 2024-05-08 | Thompson Peter A. Director, 10% Owner | Purchase | +2,841,769 | +100.00%2,841,769 | $0.88 | $2,499,856 | View SEC filing | |
| 2024-05-08 | ORBIMED ADVISORS LLC Director, 10% Owner | Purchase | +2,841,769 | +100.00%2,841,769 | $0.88 | $2,499,856 | View SEC filing | |
| 2024-05-07 | Jones William Benton See Remarks | Purchase | +39,357 | +29.42%173,130 | $0.88 | $34,624 | View SEC filing | |
| 2024-05-07 | MILLER RICHARD A MD President and CEO | Purchase | +1,136,707 | +100.00%1,136,707 | $0.88 | $1,000,000 | View SEC filing | |
| 2023-05-16 | Grais Linda Director | Purchase | +10,000 | +100.00%10,000 | $2.45 | $24,500 | View SEC filing | |
| 2022-12-20 | Jones William Benton See Remarks | Purchase | +20,000 | +17.58%133,773 | $0.79 | $15,800 | View SEC filing | |
| 2022-12-15 | LEA LEIV Chief Financial Officer | Purchase | +34,000 | +34.26%133,238 | $0.75 | $25,639 | View SEC filing | |
| 2022-12-15 | MILLER RICHARD A MD President and CEO | Purchase | +60,000 | +4.20%1,490,119 | $0.75 | $44,827 | View SEC filing | |
| 2022-09-28 | MILLER RICHARD A MD President and CEO | Purchase | +25,000 | +1.83%1,394,405 | $0.76 | $19,070 | View SEC filing | |
| 2022-09-20 | MILLER RICHARD A MD President and CEO | Purchase | +20,000 | +1.48%1,369,405 | $0.81 | $16,253 | View SEC filing | |
| 2022-06-28 | MILLER RICHARD A MD President and CEO | Purchase | +10,000 | +0.75%1,349,405 | $1.01 | $10,135 | View SEC filing | |
| 2022-06-06 | MILLER RICHARD A MD President and CEO | Purchase | +5,890 | +0.44%1,339,405 | $0.98 | $5,797 | View SEC filing | |
| 2022-04-01 | MILLER RICHARD A MD President and CEO | Purchase | +15,000 | +1.14%1,333,515 | $1.64 | $24,534 | View SEC filing | |
| 2022-03-17 | LEA LEIV Chief Financial Officer | Purchase | +49,038 | +97.69%99,238 | $1.57 | $77,045 | View SEC filing | |
| 2022-03-17 | MILLER RICHARD A MD President and CEO | Purchase | +30,000 | +2.33%1,318,515 | $1.49 | $44,600 | View SEC filing | |
| 2021-10-01 | EcoR1 Capital, LLC 10% Owner | Sale | -5,000,000 | -98.40%81,077 | $5.01 | $25,059,900 | View SEC filing | |
| 2021-09-22 | ORBIMED ADVISORS LLC Director, 10% Owner | Sale | -1,109,644 | -13.78%6,943,654 | $6.09 | $6,757,732 | View SEC filing | |
| 2021-09-22 | Thompson Peter A. Director, 10% Owner | Sale | -1,109,644 | -13.78%6,943,654 | $6.09 | $6,757,732 | View SEC filing | |
| 2021-08-23 | MILLER RICHARD A MD President and CEO | Purchase | +10,000 | +0.78%1,288,515 | $1.93 | $19,254 | View SEC filing | |
| 2021-05-05 | MILLER RICHARD A MD President and CEO | Purchase | +35,714 | +100.00%35,714 | $2.80 | $99,999 | View SEC filing | |
| 2021-02-19 | ORBIMED ADVISORS LLC Director, 10% Owner | Purchase | +1,285,714 | +19.00%8,053,298 | $3.50 | $4,499,999 | View SEC filing |
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