| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-06-02 | Randhawa Simrat EVP, Head of R&D | Sale | -26,530 | -86.90%4,000 | $90.62 | $2,404,077 | View SEC filing | |
| 2026-05-11 | Soteropoulos Paula Director | Sale | -599 | -100.00%0 | $85.47 | $51,197 | View SEC filing | |
| 2026-04-10 | Savitz Ryan EVP, CFO & CBO | Sale | -8,224 | -100.00%0 | $89.84 | $738,844 | View SEC filing | |
| 2026-04-01 | Savitz Ryan EVP, CFO & CBO | Sale | -114,367 | -100.00%0 | $83.00 | $9,492,596 | View SEC filing | |
| 2026-04-01 | Soteropoulos Paula Director | Sale | -599 | -100.00%0 | $80.11 | $47,986 | View SEC filing | |
| 2026-03-26 | Soteropoulos Paula Director | Sale | -27,594 | -100.00%0 | $78.05 | $2,153,712 | View SEC filing | |
| 2026-03-13 | Randhawa Simrat EVP, Head of R&D | Sale | -33,830 | -100.00%0 | $81.48 | $2,756,468 | View SEC filing | |
| 2026-03-13 | Garcia Marino CEO AND PRESIDENT | Sale | -122,918 | -100.00%0 | $81.49 | $10,016,381 | View SEC filing | |
| 2026-03-13 | CARR EDWARD CHIEF ACCOUNTING OFFICER | Sale | -43,682 | -100.00%0 | $81.49 | $3,559,495 | View SEC filing | |
| 2025-12-05 | Savitz Ryan CFO & CBO | Sale | -20,000 | -100.00%0 | $45.18 | $903,600 | View SEC filing | |
| 2025-11-14 | Randhawa Simrat EVP, Head of R&D | Sale | -196,538 | -95.63%4,000 | $37.55 | $7,379,887 | View SEC filing | |
| 2025-09-11 | Savitz Ryan CFO & CBO | Sale | -20,000 | -100.00%0 | $35.00 | $700,000 | View SEC filing | |
| 2023-10-03 | Harwin Peter Evan Director, 10% Owner | Purchase | +24,670 | +1.30%1,928,503 | $13.63 | $336,252 | View SEC filing | |
| 2023-09-28 | Harwin Peter Evan Director, 10% Owner | Purchase | +30,000 | +1.60%1,903,833 | $13.15 | $394,500 | View SEC filing | |
| 2023-09-25 | Randhawa Simrat Chief Medical Officer | Purchase | +4,000 | +100.00%4,000 | $13.20 | $52,800 | View SEC filing | |
| 2023-09-21 | Harwin Peter Evan Director, 10% Owner | Purchase | +30,000 | +1.63%1,873,833 | $13.20 | $396,000 | View SEC filing | |
| 2023-09-13 | Harwin Peter Evan Director, 10% Owner | Purchase | +24,254 | +1.33%1,843,833 | $11.20 | $271,680 | View SEC filing | |
| 2023-02-09 | TRV GP IV, LLC 10% Owner | Sale | -3,700,000 | -54.75%3,058,204 | $0.83 | $3,056,000 | View SEC filing | |
| 2021-09-20 | Stants Kristen Chief People Officer | Sale | -5,736 | -28.68%14,264 | $6.73 | $38,603 | View SEC filing | |
| 2021-09-20 | Mahoney Stephen F. See Remarks | Sale | -5,736 | -28.68%14,264 | $6.73 | $38,603 | View SEC filing | |
| 2021-09-20 | Deardorf Caren Chief Commercial Officer | Sale | -6,238 | -31.19%13,762 | $6.73 | $41,982 | View SEC filing | |
| 2021-09-20 | GARDNER JASON See Remarks | Sale | -14,340 | -4.76%286,872 | $6.73 | $96,508 | View SEC filing | |
| 2021-09-20 | Beetham Thomas W. See Remarks | Sale | -6,103 | -30.51%13,897 | $6.73 | $41,073 | View SEC filing | |
| 2021-09-20 | Olson Lisa See Remarks | Sale | -5,736 | -28.68%14,264 | $6.73 | $38,603 | View SEC filing | |
| 2021-09-20 | Nichols David Wayne Chief Technical Officer | Sale | -5,694 | -28.47%14,306 | $6.73 | $38,321 | View SEC filing |
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