| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-05-19 | Graves Adrienne L Director | Purchase | +1,000 | +100.00%1,000 | $31.07 | $31,070 | View SEC filing | |
| 2026-05-19 | SILVERNAIL LAUREN P Director | Purchase | +1,000 | +100.00%1,000 | $31.00 | $31,000 | View SEC filing | |
| 2026-03-05 | Opaleye Management Inc. 10% Owner | Sale | -198,572 | -5.12%3,681,428 | $39.51 | $7,846,426 | View SEC filing | |
| 2026-03-03 | Opaleye Management Inc. 10% Owner | Sale | -5,000 | -7.14%65,000 | $54.18 | $270,900 | View SEC filing | |
| 2026-01-08 | Opaleye Management Inc. 10% Owner | Sale | -20,000 | -22.22%70,000 | $53.35 | $1,066,914 | View SEC filing | |
| 2025-06-11 | Opaleye Management Inc. 10% Owner | Sale | -30,204 | -25.13%90,000 | $30.59 | $923,827 | View SEC filing | |
| 2025-06-05 | Opaleye Management Inc. 10% Owner | Sale | -4,796 | -3.84%120,204 | $30.03 | $144,024 | View SEC filing | |
| 2025-05-14 | Opaleye Management Inc. 10% Owner | Sale | -15,000 | -10.71%125,000 | $26.13 | $391,904 | View SEC filing | |
| 2025-05-14 | Opaleye Management Inc. 10% Owner | Sale | -5,000 | -3.33%145,000 | $29.64 | $148,200 | View SEC filing | |
| 2025-05-14 | Opaleye Management Inc. 10% Owner | Sale | -5,000 | -3.45%140,000 | $30.01 | $150,055 | View SEC filing | |
| 2025-03-26 | Opaleye Management Inc. 10% Owner | Sale | -5,000 | -3.45%140,000 | $30.01 | $150,055 | View SEC filing | |
| 2025-03-20 | Opaleye Management Inc. 10% Owner | Sale | -5,000 | -3.33%145,000 | $29.64 | $148,200 | View SEC filing | |
| 2025-03-04 | Opaleye Management Inc. 10% Owner | Sale | -5,000 | -3.23%150,000 | $28.05 | $140,250 | View SEC filing | |
| 2025-01-24 | Opaleye Management Inc. 10% Owner | Sale | -20,000 | -11.43%155,000 | $35.59 | $711,814 | View SEC filing | |
| 2024-04-25 | Opaleye Management Inc. 10% Owner | Purchase | +20,000 | +0.53%3,815,000 | $9.97 | $199,400 | View SEC filing | |
| 2024-04-24 | Opaleye Management Inc. 10% Owner | Purchase | +20,000 | +0.53%3,795,000 | $10.23 | $204,640 | View SEC filing | |
| 2024-04-19 | Opaleye Management Inc. 10% Owner | Purchase | +29,400 | +0.78%3,775,000 | $10.56 | $310,391 | View SEC filing | |
| 2024-03-28 | Opaleye Management Inc. 10% Owner | Purchase | +50,000 | +1.35%3,745,600 | $12.82 | $641,000 | View SEC filing | |
| 2024-03-25 | BAUM MARK L CHIEF EXECUTIVE OFFICER | Purchase | +9,000 | +0.42%2,137,525 | $11.59 | $104,310 | View SEC filing | |
| 2024-03-22 | Opaleye Management Inc. 10% Owner | Purchase | +50,600 | +1.39%3,695,600 | $9.65 | $488,290 | View SEC filing | |
| 2023-11-16 | BAUM MARK L Chief Executive Officer | Purchase | +7,500 | +0.37%2,022,961 | $8.11 | $60,825 | View SEC filing | |
| 2023-11-16 | Opaleye Management Inc. 10% Owner | Purchase | +25,000 | +0.69%3,645,000 | $8.03 | $200,735 | View SEC filing | |
| 2023-09-20 | Opaleye Management Inc. 10% Owner | Purchase | +20,000 | +0.56%3,620,000 | $14.60 | $292,076 | View SEC filing | |
| 2023-08-15 | BAUM MARK L Chief Executive Officer | Purchase | +5,800 | +0.29%2,015,461 | $17.05 | $98,890 | View SEC filing | |
| 2023-08-15 | Makary Martin A. Director | Purchase | +20,000 | +80.00%45,000 | $16.92 | $338,400 | View SEC filing |
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