| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-01-12 | Borthwick Kathleen CFO | Sale | -2,062 | -27.63%5,402 | $18.44 | $38,022 | View SEC filing | |
| 2026-01-12 | Chou William PRESIDENT AND CEO | Sale | -4,076 | -38.45%6,524 | $18.44 | $75,159 | View SEC filing | |
| 2025-09-15 | Nichols Weston 10% Owner | Purchase | +32,008 | +2.70%1,215,725 | $6.99 | $223,735 | View SEC filing | |
| 2025-07-24 | Nichols Weston 10% Owner | Purchase | +128,848 | +13.72%1,067,667 | $5.70 | $733,826 | View SEC filing | |
| 2025-06-26 | ORBIMED ADVISORS LLC 10% Owner | Sale | -583,657 | -8.78%6,066,343 | $0.34 | $197,239 | View SEC filing | |
| 2025-04-24 | ORBIMED ADVISORS LLC 10% Owner | Sale | -235,572 | -3.42%6,650,000 | $0.33 | $78,731 | View SEC filing | |
| 2025-04-17 | ORBIMED ADVISORS LLC 10% Owner | Sale | -149,054 | -2.12%6,885,572 | $0.33 | $49,704 | View SEC filing | |
| 2025-02-12 | Borthwick Kathleen CFO | Sale | -3,183 | -7.16%41,283 | $0.53 | $1,686 | View SEC filing | |
| 2025-01-14 | ORBIMED ADVISORS LLC 10% Owner | Sale | -223,219 | -3.08%7,034,626 | $0.64 | $142,223 | View SEC filing | |
| 2025-01-08 | ORBIMED ADVISORS LLC 10% Owner | Sale | -147,024 | -1.99%7,257,845 | $0.70 | $103,306 | View SEC filing | |
| 2024-12-31 | Nichols Weston 10% Owner | Purchase | +373,645 | +4.21%9,256,953 | $0.65 | $241,038 | View SEC filing | |
| 2024-12-26 | ORBIMED ADVISORS LLC 10% Owner | Sale | -230,321 | -3.02%7,404,869 | $0.60 | $138,193 | View SEC filing | |
| 2024-12-11 | ORBIMED ADVISORS LLC 10% Owner | Sale | -62,276 | -0.81%7,635,190 | $0.83 | $51,988 | View SEC filing | |
| 2024-12-06 | ORBIMED ADVISORS LLC 10% Owner | Sale | -97,103 | -1.25%7,697,466 | $0.80 | $77,338 | View SEC filing | |
| 2024-11-27 | Nichols Weston 10% Owner | Purchase | +456,353 | +2.67%17,570,261 | $0.62 | $284,520 | View SEC filing | |
| 2024-09-23 | ORBIMED ADVISORS LLC 10% Owner | Sale | -39,300 | -0.50%7,794,569 | $0.71 | $27,903 | View SEC filing | |
| 2024-09-18 | ORBIMED ADVISORS LLC 10% Owner | Sale | -200,131 | -2.49%7,833,869 | $0.73 | $146,727 | View SEC filing | |
| 2024-02-13 | Borthwick Kathleen SVP, INTERIM CFO | Sale | -1,470 | -4.91%28,466 | $0.97 | $1,426 | View SEC filing | |
| 2024-02-13 | Forman Mark S CHIEF MEDICAL OFFICER | Sale | -1,638 | -3.26%48,631 | $0.97 | $1,589 | View SEC filing | |
| 2024-01-03 | Forman Mark S Chief Medical Officer | Sale | -15,813 | -25.89%45,269 | $0.91 | $14,390 | View SEC filing | |
| 2024-01-03 | Borthwick Kathleen SVP, Interim CFO | Sale | -10,672 | -29.15%25,936 | $0.91 | $9,712 | View SEC filing | |
| 2024-01-03 | Cale Edgar B. GC & Corporate Secretary | Sale | -15,813 | -25.58%45,995 | $0.91 | $14,390 | View SEC filing | |
| 2023-08-01 | King Simona Chief Financial Officer | Sale | -11,453 | -32.31%23,994 | $0.88 | $10,079 | View SEC filing | |
| 2023-06-29 | ORBIMED ADVISORS LLC 10% Owner | Purchase | +1,192,577 | +17.43%8,034,000 | $0.84 | $1,001,765 | View SEC filing | |
| 2023-06-20 | Fotopoulos Alexandros Chief Technical Officer | Sale | -4,052 | -12.37%28,693 | $0.93 | $3,778 | View SEC filing |
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