| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-06-01 | Xu Diyong Director, 10% Owner | Purchase | +1,875,000 | -72.26%625,000 | $8.00 | $15,000,000 | View SEC filing | |
| 2026-06-01 | ORBIMED ADVISORS LLC Director, 10% Owner | Purchase | +1,875,000 | -72.26%625,000 | $8.00 | $15,000,000 | View SEC filing | |
| 2026-02-27 | Kalowski Lee CFO and President | Sale | -3,995 | -10.00%35,943 | $4.51 | $18,035 | View SEC filing | |
| 2026-02-27 | Morrison Jodie Pope CEO | Sale | -9,896 | -10.00%89,104 | $4.51 | $44,675 | View SEC filing | |
| 2026-02-27 | Violette Shelia M. Chief Scientific Officer | Sale | -2,815 | -4.82%55,569 | $4.51 | $12,708 | View SEC filing | |
| 2025-12-04 | Morrison Jodie Pope CEO | Sale | -22,506 | -18.52%99,000 | $3.46 | $77,871 | View SEC filing | |
| 2025-12-04 | Kalowski Lee CFO and President | Sale | -9,072 | -18.51%39,938 | $3.46 | $31,395 | View SEC filing | |
| 2025-08-28 | Morrison Jodie Pope CEO | Sale | -10,494 | -7.95%121,506 | $1.80 | $18,900 | View SEC filing | |
| 2025-08-28 | Violette Shelia M. Chief Scientific Officer | Sale | -2,990 | -4.87%58,384 | $1.80 | $5,385 | View SEC filing | |
| 2025-08-28 | Kalowski Lee CFO and President | Sale | -4,240 | -7.96%49,010 | $1.80 | $7,636 | View SEC filing | |
| 2024-08-14 | TZIANABOS ARTHUR Director | Sale | -265 | -3.21%7,983 | $24.20 | $6,413 | View SEC filing | |
| 2024-04-23 | Alloway Paul See Remarks | Sale | -268 | -9.36%2,596 | $24.21 | $6,488 | View SEC filing | |
| 2024-04-23 | Michaud Charles Jr See Remarks | Sale | -75 | -7.49%927 | $24.20 | $1,815 | View SEC filing | |
| 2024-02-15 | TZIANABOS ARTHUR Director | Sale | -13,037 | -9.19%128,778 | $0.57 | $7,445 | View SEC filing | |
| 2024-01-05 | Alloway Paul See Remarks | Sale | -7,280 | -20.61%28,036 | $0.57 | $4,120 | View SEC filing | |
| 2024-01-05 | Michaud Charles Jr See Remarks | Sale | -1,708 | -12.84%11,598 | $0.57 | $975 | View SEC filing | |
| 2023-09-08 | Seymour Albert See Remarks | Sale | -1,448 | -0.95%150,874 | $1.15 | $1,665 | View SEC filing | |
| 2023-08-07 | Jordan Julie Chief Medical Officer | Sale | -1,853 | +73.60%7,496 | $1.39 | $2,576 | View SEC filing | |
| 2023-08-04 | Jordan Julie Chief Medical Officer | Sale | -99 | -3.45%2,770 | $1.31 | $130 | View SEC filing | |
| 2023-03-06 | Alloway Paul See Remarks | Sale | -10,965 | -39.63%16,706 | $1.45 | $15,863 | View SEC filing | |
| 2023-01-11 | Blum Michael Lee Chief Commercial Officer | Sale | -2,454 | -15.35%13,538 | $1.39 | $3,412 | View SEC filing | |
| 2023-01-11 | Alloway Paul See Remarks | Sale | -3,090 | -13.32%20,103 | $1.39 | $4,296 | View SEC filing | |
| 2023-01-11 | Smith W Bradford See Remarks | Sale | -3,729 | -20.78%14,219 | $1.39 | $5,188 | View SEC filing | |
| 2023-01-11 | Seymour Albert See Remarks | Sale | -3,620 | -2.47%143,166 | $1.39 | $5,033 | View SEC filing | |
| 2023-01-11 | TZIANABOS ARTHUR Director | Sale | -10,616 | -8.92%108,395 | $1.39 | $14,762 | View SEC filing |
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