| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-06-15 | Horn Margaret A Chief Operating Officer | Sale | -10,000 | -5.94%158,222 | $148.01 | $1,480,139 | View SEC filing | |
| 2026-05-28 | Mancini Anthony See Remarks | Sale | -3,121 | -5.43%54,400 | $153.99 | $480,611 | View SEC filing | |
| 2026-04-27 | Mancini Anthony See Remarks | Sale | -3,120 | -5.42%54,400 | $132.41 | $413,129 | View SEC filing | |
| 2026-04-17 | GOLDSMITH MARK A See Remarks | Sale | -120,000 | -30.25%276,698 | $150.09 | $18,010,488 | View SEC filing | |
| 2026-03-26 | Mancini Anthony See Remarks | Sale | -37,450 | -40.77%54,400 | $95.56 | $3,578,821 | View SEC filing | |
| 2026-03-19 | Wei Lin Chief Medical Officer | Sale | -2,073 | -2.00%101,366 | $99.48 | $206,223 | View SEC filing | |
| 2026-03-19 | Kelsey Stephen Michael See Remarks | Sale | -4,302 | -1.44%295,398 | $99.48 | $427,965 | View SEC filing | |
| 2026-03-19 | GOLDSMITH MARK A See Remarks | Sale | -12,871 | -4.44%276,698 | $99.48 | $1,280,412 | View SEC filing | |
| 2026-03-19 | Horn Margaret A Chief Operating Officer | Sale | -4,583 | -2.83%157,570 | $99.48 | $455,919 | View SEC filing | |
| 2026-03-19 | Anders Jack Chief Financial Officer | Sale | -2,753 | -2.15%125,512 | $99.48 | $273,870 | View SEC filing | |
| 2026-03-19 | Cislini Jeff General Counsel | Sale | -2,958 | -4.81%58,518 | $98.68 | $291,890 | View SEC filing | |
| 2026-03-19 | Wang Xiaolin See Remarks | Sale | -2,010 | -1.70%116,063 | $99.48 | $199,956 | View SEC filing | |
| 2026-03-03 | GOLDSMITH MARK A See Remarks | Sale | -36,000 | -8.53%353,993 | $101.23 | $3,644,354 | View SEC filing | |
| 2026-01-23 | Cislini Jeff General Counsel | Sale | -908 | -1.90%46,976 | $115.60 | $104,965 | View SEC filing | |
| 2026-01-09 | Horn Margaret A Chief Operating Officer | Sale | -75,000 | -34.71%141,053 | $100.56 | $7,542,023 | View SEC filing | |
| 2026-01-09 | Anders Jack Chief Financial Officer | Sale | -10,000 | -8.47%108,065 | $98.00 | $980,000 | View SEC filing | |
| 2025-12-18 | Cislini Jeff General Counsel | Sale | -2,688 | -5.32%47,884 | $76.82 | $206,484 | View SEC filing | |
| 2025-12-18 | GOLDSMITH MARK A See Remarks | Sale | -15,394 | -6.21%232,469 | $76.82 | $1,182,526 | View SEC filing | |
| 2025-12-18 | Kelsey Stephen Michael See Remarks | Sale | -5,447 | -1.92%278,600 | $76.82 | $418,423 | View SEC filing | |
| 2025-12-18 | Horn Margaret A Chief Operating Officer | Sale | -4,847 | -3.32%141,053 | $76.82 | $372,333 | View SEC filing | |
| 2025-12-18 | Anders Jack Chief Financial Officer | Sale | -3,104 | -2.79%108,065 | $77.09 | $239,289 | View SEC filing | |
| 2025-11-26 | Anders Jack Chief Financial Officer | Sale | -5,418 | -4.65%110,994 | $74.00 | $400,932 | View SEC filing | |
| 2025-11-26 | GOLDSMITH MARK A See Remarks | Sale | -66,000 | -16.65%315,287 | $75.08 | $4,954,962 | View SEC filing | |
| 2025-11-20 | GOLDSMITH MARK A See Remarks | Sale | -20,000 | -7.47%247,863 | $70.38 | $1,407,586 | View SEC filing | |
| 2025-11-20 | Cislini Jeff General Counsel | Sale | -13,388 | -20.98%50,425 | $70.14 | $939,008 | View SEC filing |
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