| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-05-04 | Opaleye Management Inc. 10% Owner | Sale | -35,581 | -3.98%858,569 | $16.14 | $574,240 | View SEC filing | |
| 2026-04-30 | Opaleye Management Inc. 10% Owner | Sale | -70,648 | -7.32%894,150 | $18.05 | $1,274,971 | View SEC filing | |
| 2026-04-21 | Opaleye Management Inc. 10% Owner | Sale | -16,469 | -1.68%964,798 | $20.46 | $336,982 | View SEC filing | |
| 2025-12-15 | MANCHESTER MANAGEMENT CO LLC Other | Sale | -20,000 | -23.81%63,999 | $27.95 | $559,066 | View SEC filing | |
| 2025-12-11 | MANCHESTER MANAGEMENT CO LLC Other | Sale | -144,810 | -14.33%865,980 | $30.73 | $4,450,061 | View SEC filing | |
| 2025-12-10 | MANCHESTER MANAGEMENT CO LLC Other | Sale | -144,810 | -14.33%865,980 | $30.73 | $4,450,061 | View SEC filing | |
| 2025-10-09 | Opaleye Management Inc. 10% Owner | Purchase | +1,267 | +0.13%966,267 | $30.28 | $38,361 | View SEC filing | |
| 2025-06-09 | Stegagno Peter Chief Operating Officer | Sale | -1,862 | -47.82%2,032 | $27.71 | $51,596 | View SEC filing | |
| 2025-05-16 | Cioanta Iulian Chief Sci. and Tech. Officer | Sale | -3,639 | -98.89%41 | $31.60 | $114,992 | View SEC filing | |
| 2025-04-30 | Opaleye Management Inc. 10% Owner | Purchase | +7,998 | +0.82%980,000 | $25.49 | $203,875 | View SEC filing | |
| 2024-11-01 | Opaleye Management Inc. 10% Owner | Purchase | +27,868 | +2.95%972,002 | $15.75 | $438,902 | View SEC filing | |
| 2024-10-23 | MANCHESTER MANAGEMENT CO LLC Other | Purchase | +181,818 | +22.04%1,006,790 | $8.25 | $1,499,999 | View SEC filing | |
| 2019-11-04 | Parikh Shri P. President | Purchase | +1,000,000 | +100.00%1,000,000 | $0.11 | $110,000 | View SEC filing | |
| 2019-08-28 | Stolarski Anthony Michael Director | Purchase | +11,036,864 | +184.73%17,011,490 | $0.11 | $1,207,305 | View SEC filing | |
| 2019-08-28 | Richardson Kevin A II Chief Executive Officer | Purchase | +5,569,910 | +351.79%7,153,226 | $0.11 | $612,690 | View SEC filing | |
| 2019-04-25 | Stolarski Anthony Michael Director | Purchase | -2,475,000 | -28.53%6,199,626 | $0.08 | $198,000 | View SEC filing | |
| 2019-04-25 | Richardson Kevin A II Director | Purchase | +137,500 | +43.65%452,500 | $0.03 | $4,593 | View SEC filing | |
| 2016-09-30 | Stolarski Anthony Michael Director | Purchase | +500,000 | +15.51%3,724,626 | $0.06 | $30,000 | View SEC filing | |
| 2014-03-19 | Chiarelli Joseph Chief Executive Officer | Purchase | +240,000 | +336.00%181,667 | $0.17 | $40,000 | View SEC filing | |
| 2014-03-18 | Richardson Kevin A II Director, 10% Owner | Purchase | +300,000 | +81.40%195,000 | $0.17 | $50,000 | View SEC filing | |
| 2013-10-09 | Chiarelli Joseph Chief Executive Officer | Purchase | +83,334 | +100.00%83,334 | $0.30 | $25,000 | View SEC filing | |
| 2013-10-09 | Richardson Kevin A II Director, 10% Owner | Purchase | +70,624 | +4.56%1,618,628 | $0.30 | $21,187 | View SEC filing | |
| 2013-09-19 | Jenkins Barry J. Chief Financial Officer | Purchase | +13,500 | +6.68%215,742 | $0.74 | $9,990 | View SEC filing | |
| 2013-08-15 | Cashman Christopher M 10% Owner | Sale | -33,500 | -13.64%212,030 | $0.77 | $25,795 | View SEC filing | |
| 2013-06-11 | Cashman Christopher M 10% Owner | Sale | -34,800 | -12.41%245,530 | $0.80 | $27,812 | View SEC filing |
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