| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2025-11-17 | EW HEALTHCARE PARTNERS FUND 2, L.P. 10% Owner, Other | Purchase | +3,604,000 | +87.67%7,714,709 | $1.11 | $4,000,440 | View SEC filing | |
| 2024-10-24 | Cuca Roberto COO and CFO | Purchase | +64,444 | +70.86%155,388 | $2.25 | $144,999 | View SEC filing | |
| 2024-10-24 | Talmo Paul Chief Technology Officer | Purchase | +22,222 | +32.27%91,082 | $2.25 | $50,000 | View SEC filing | |
| 2024-10-24 | KOBLISH ANTONY Chief Executive Officer | Purchase | +88,888 | +24.02%458,897 | $2.25 | $199,998 | View SEC filing | |
| 2024-10-24 | Firestone Gregory A. Chief Commercial Officer | Purchase | +6,666 | +13.17%57,279 | $2.25 | $14,999 | View SEC filing | |
| 2024-07-02 | ORBIMED ADVISORS LLC 10% Owner | Sale | -428,300 | -15.10%2,407,242 | $4.72 | $2,022,000 | View SEC filing | |
| 2024-02-16 | EW HEALTHCARE PARTNERS FUND 2, L.P. 10% Owner, Other | Purchase | +326,062 | +212.82%3,610,709 | $9.32 | $3,038,315 | View SEC filing | |
| 2023-12-07 | Firestone Gregory A. Chief Business Officer | Purchase | +2,600 | +7.90%35,511 | $5.65 | $14,688 | View SEC filing | |
| 2023-11-14 | Cuca Roberto COO and CFO | Purchase | +10,000 | +19.09%62,371 | $4.49 | $44,938 | View SEC filing | |
| 2023-11-14 | KOBLISH ANTONY Chief Executive Officer | Purchase | +11,000 | +3.76%303,634 | $4.54 | $49,976 | View SEC filing | |
| 2023-04-21 | ORBIMED ADVISORS LLC 10% Owner | Sale | -192,000 | -6.34%2,835,542 | $9.34 | $1,792,326 | View SEC filing | |
| 2022-11-04 | Opaleye Management Inc. 10% Owner | Purchase | +20,262 | +0.99%2,072,813 | $7.81 | $158,285 | View SEC filing | |
| 2022-10-11 | Opaleye Management Inc. 10% Owner | Purchase | +16,000 | +0.79%2,052,551 | $8.00 | $128,000 | View SEC filing | |
| 2022-09-26 | Opaleye Management Inc. 10% Owner | Purchase | +6,804 | +0.34%2,036,551 | $7.99 | $54,393 | View SEC filing | |
| 2022-09-19 | Opaleye Management Inc. 10% Owner | Purchase | +18,000 | +0.89%2,029,747 | $8.09 | $145,584 | View SEC filing | |
| 2022-09-16 | Opaleye Management Inc. 10% Owner | Purchase | +6,530 | +0.33%2,011,747 | $8.09 | $52,853 | View SEC filing | |
| 2022-09-15 | Opaleye Management Inc. 10% Owner | Purchase | +5,221 | +0.26%2,005,217 | $8.10 | $42,285 | View SEC filing | |
| 2022-08-19 | EW HEALTHCARE PARTNERS FUND 2, L.P. Other | Purchase | +500,000 | +13.87%4,105,709 | $8.00 | $4,000,000 | View SEC filing | |
| 2022-08-16 | Opaleye Management Inc. 10% Owner | Purchase | +315,000 | +18.69%2,000,000 | $8.00 | $2,520,000 | View SEC filing | |
| 2022-08-12 | Opaleye Management Inc. 10% Owner | Purchase | +4,979 | +0.30%1,669,179 | $7.96 | $39,632 | View SEC filing | |
| 2022-08-12 | Opaleye Management Inc. 10% Owner | Purchase | +11,979 | +0.72%1,685,000 | $8.52 | $102,089 | View SEC filing | |
| 2022-08-02 | Opaleye Management Inc. 10% Owner | Purchase | +4,979 | +0.30%1,666,179 | $7.96 | $39,632 | View SEC filing | |
| 2022-07-22 | Opaleye Management Inc. 10% Owner | Purchase | +5,200 | +0.31%1,664,200 | $8.02 | $41,709 | View SEC filing | |
| 2022-07-21 | Opaleye Management Inc. 10% Owner | Purchase | +10,333 | +0.63%1,659,000 | $8.03 | $83,010 | View SEC filing | |
| 2022-07-20 | Opaleye Management Inc. 10% Owner | Purchase | +5,100 | +0.31%1,648,667 | $8.08 | $41,192 | View SEC filing |
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