| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-06-03 | Crystal Adam President, R&D | Sale | -27,000 | -18.92%115,743 | $22.87 | $617,571 | View SEC filing | |
| 2026-05-05 | Crystal Adam President, R&D | Sale | -27,000 | -18.92%115,743 | $21.23 | $573,097 | View SEC filing | |
| 2026-04-16 | Crystal Adam President, R&D | Sale | -38,460 | -25.46%112,622 | $25.00 | $961,500 | View SEC filing | |
| 2026-04-02 | Crystal Adam President, R&D | Sale | -27,000 | -19.34%112,622 | $21.20 | $572,478 | View SEC filing | |
| 2026-03-27 | Crystal Adam President, R&D | Sale | -12,000 | -9.63%112,622 | $20.11 | $241,320 | View SEC filing | |
| 2026-03-09 | Crystal Adam President, R&D | Sale | -20,251 | -15.24%112,622 | $15.00 | $303,765 | View SEC filing | |
| 2026-02-27 | Crystal Adam President, R&D | Sale | -54,345 | -29.03%132,873 | $12.77 | $694,208 | View SEC filing | |
| 2026-02-04 | Beckman Daniella Chief Financial Officer | Sale | -10,317 | -5.30%184,297 | $12.26 | $126,531 | View SEC filing | |
| 2026-02-04 | Weber Barbara Director, Executive Chair | Sale | -30,519 | -1.84%1,629,254 | $12.26 | $374,294 | View SEC filing | |
| 2026-02-04 | Crystal Adam President, R&D | Sale | -18,452 | -8.97%187,218 | $12.26 | $226,300 | View SEC filing | |
| 2025-10-27 | TRV GP IV, LLC 10% Owner | Sale | -477,401 | -3.44%13,386,574 | $10.15 | $4,846,575 | View SEC filing | |
| 2025-09-29 | TRV GP IV, LLC 10% Owner | Sale | -500,000 | -3.48%13,863,975 | $8.02 | $4,008,500 | View SEC filing | |
| 2025-09-17 | TRV GP IV, LLC 10% Owner | Sale | -363,541 | -2.47%14,363,975 | $7.04 | $2,559,329 | View SEC filing | |
| 2025-09-09 | TRV GP IV, LLC 10% Owner | Sale | -729,365 | -4.72%14,727,516 | $7.00 | $5,108,970 | View SEC filing | |
| 2025-08-26 | TRV GP IV, LLC 10% Owner | Sale | -302,194 | -1.92%15,456,881 | $7.00 | $2,115,358 | View SEC filing | |
| 2025-08-21 | TRV GP IV, LLC 10% Owner | Sale | -1,100,000 | -6.52%15,759,075 | $7.01 | $7,712,760 | View SEC filing | |
| 2025-02-06 | Barry Douglas General Counsel | Sale | -5,330 | -7.47%66,014 | $3.07 | $16,369 | View SEC filing | |
| 2025-02-06 | Beckman Daniella Chief Financial Officer | Sale | -8,232 | -5.19%150,284 | $3.07 | $25,282 | View SEC filing | |
| 2025-02-06 | Crystal Adam See Remarks | Sale | -14,283 | -8.28%158,210 | $3.07 | $43,866 | View SEC filing | |
| 2025-02-06 | Weber Barbara Chief Executive Officer | Sale | -18,791 | -1.15%1,622,251 | $3.07 | $57,710 | View SEC filing | |
| 2024-11-18 | Rothenberg Mace Director | Purchase | +20,000 | +177.78%31,250 | $3.70 | $74,000 | View SEC filing | |
| 2024-11-08 | EcoR1 Capital, LLC 10% Owner | Sale | -2,700,000 | -20.25%10,630,736 | $3.12 | $8,435,743 | View SEC filing | |
| 2024-11-07 | Davis Aaron I. Other | Sale | -3,080,000 | -46.03%3,610,642 | $3.14 | $9,671,200 | View SEC filing | |
| 2024-10-28 | Davis Aaron I. Other | Sale | -633,000 | -8.64%6,690,642 | $6.87 | $4,348,710 | View SEC filing | |
| 2024-10-23 | Davis Aaron I. Other | Sale | -875,000 | -10.67%7,323,642 | $6.97 | $6,101,250 | View SEC filing |
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