| Filing Date | Insider | Type | 10b5-1 | Net Shares | Ownership change | Avg. Price | Value | Filing |
|---|---|---|---|---|---|---|---|---|
| 2026-05-19 | Coughlin Timothy Director | Sale | -3,250 | -5.86%52,250 | $43.49 | $141,343 | View SEC filing | |
| 2026-05-06 | Cline Christopher R. CHIEF FINANCIAL OFFICER | Sale | -2,491 | -2.06%118,658 | $46.31 | $115,368 | View SEC filing | |
| 2026-05-06 | Inrig Jula CHIEF MEDICAL OFFICER | Sale | -22,485 | -13.87%113,238 | $45.15 | $1,015,086 | View SEC filing | |
| 2026-05-06 | Heerma Peter CHIEF COMMERCIAL OFFICER | Sale | -2,174 | -1.52%140,684 | $46.65 | $101,417 | View SEC filing | |
| 2026-05-06 | Dube Eric M CHIEF EXECUTIVE OFFICER | Sale | -22,500 | -4.94%432,886 | $43.95 | $988,875 | View SEC filing | |
| 2026-05-06 | ROTE WILLIAM E. Chief Research Officer | Sale | -2,763 | -2.34%115,474 | $43.95 | $121,434 | View SEC filing | |
| 2026-05-06 | Baynes Roy D. Director | Sale | -4,500 | -10.71%37,500 | $46.65 | $209,925 | View SEC filing | |
| 2026-05-06 | Meckler Jeffrey A Director | Sale | -8,000 | -8.38%87,500 | $45.00 | $360,000 | View SEC filing | |
| 2026-05-06 | REED ELIZABETH E Chief Legal Officer and GC | Sale | -24,250 | -15.97%105,211 | $45.06 | $1,092,657 | View SEC filing | |
| 2026-05-04 | Baynes Roy D. Director | Sale | -9,750 | -20.63%37,500 | $44.22 | $431,145 | View SEC filing | |
| 2026-04-23 | ROTE WILLIAM E. Chief Research Officer | Sale | -9,100 | -7.39%113,987 | $39.09 | $355,719 | View SEC filing | |
| 2026-04-16 | Calvin Sandra SVP, CHIEF ACCOUNTING OFFICER | Sale | -21,977 | -34.16%42,353 | $41.07 | $902,595 | View SEC filing | |
| 2026-04-16 | Baynes Roy D. Director | Sale | -32,750 | -46.62%37,500 | $41.29 | $1,352,130 | View SEC filing | |
| 2026-04-16 | LYONS GARY A Director | Sale | -8,000 | -12.21%57,500 | $41.07 | $328,560 | View SEC filing | |
| 2026-04-15 | Cline Christopher R. CHIEF FINANCIAL OFFICER | Sale | -8,327 | -6.65%116,899 | $41.91 | $348,974 | View SEC filing | |
| 2026-04-15 | Inrig Jula CHIEF MEDICAL OFFICER | Sale | -8,233 | -6.88%111,473 | $42.01 | $345,893 | View SEC filing | |
| 2026-04-15 | Heerma Peter CHIEF COMMERCIAL OFFICER | Sale | -7,215 | -4.95%138,608 | $41.93 | $302,516 | View SEC filing | |
| 2026-04-15 | Dube Eric M CHIEF EXECUTIVE OFFICER | Sale | -64,000 | -12.88%432,886 | $41.09 | $2,629,975 | View SEC filing | |
| 2026-04-15 | REED ELIZABETH E Chief Legal Officer and GC | Sale | -51,500 | -32.86%105,211 | $41.29 | $2,126,452 | View SEC filing | |
| 2026-04-07 | Baynes Roy D. Director | Sale | -10,000 | -21.05%37,500 | $33.00 | $330,000 | View SEC filing | |
| 2026-04-02 | Dube Eric M CHIEF EXECUTIVE OFFICER | Sale | -60,000 | -12.17%432,886 | $30.93 | $1,855,839 | View SEC filing | |
| 2026-04-02 | REED ELIZABETH E Chief Legal Officer and GC | Sale | -10,000 | -8.68%105,211 | $30.00 | $300,000 | View SEC filing | |
| 2026-03-18 | REED ELIZABETH E Chief Legal Officer and GC | Sale | -10,000 | -8.68%105,211 | $28.09 | $280,861 | View SEC filing | |
| 2026-02-24 | Dube Eric M CHIEF EXECUTIVE OFFICER | Sale | -60,000 | -12.17%432,886 | $30.10 | $1,805,766 | View SEC filing | |
| 2026-02-19 | REED ELIZABETH E Chief Legal Officer and GC | Sale | -10,000 | -8.68%105,211 | $27.83 | $278,315 | View SEC filing |
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